Detalhe da pesquisa
1.
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol.
Environ Sci Technol
; 58(16): 6913-6923, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593436
2.
Rifabutin but not rifampicin can partly out-balance P-glycoprotein induction by concurrent P-glycoprotein inhibition through high affinity binding to the inhibitory site.
Arch Toxicol
; 98(1): 223-231, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833491
3.
Dietary phytochemicals as modulators of human pregnane X receptor.
Crit Rev Food Sci Nutr
; 63(19): 3279-3301, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-34698593
4.
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors.
Bioconjug Chem
; 33(10): 1825-1836, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36197842
5.
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids.
Arch Toxicol
; 96(1): 195-210, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34689256
6.
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism.
Arch Toxicol
; 95(1): 11-25, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33164107
7.
Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis.
Int J Mol Sci
; 22(12)2021 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34208774
8.
ß-catenin signaling, the constitutive androstane receptor and their mutual interactions.
Arch Toxicol
; 94(12): 3983-3991, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097968
9.
Marine Ligands of the Pregnane X Receptor (PXR): An Overview.
Mar Drugs
; 17(10)2019 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31569349
10.
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver.
Int J Mol Sci
; 20(18)2019 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31540101
11.
Effect of Endocannabinoid Oleamide on Rat and Human Liver Cytochrome P450 Enzymes in In Vitro and In Vivo Models.
Drug Metab Dispos
; 46(6): 913-923, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650790
12.
Honey flavonoids inhibit hOATP2B1 and hOATP1A2 transporters and hOATP-mediated rosuvastatin cell uptake in vitro.
Xenobiotica
; 48(7): 745-755, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28745105
13.
Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction.
Int J Mol Sci
; 19(6)2018 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914136
14.
The plausible association of MTHFR and ADORA2A polymorphisms with nodules in rheumatoid arthritis patients treated with methotrexate.
Pharmacogenet Genomics
; 27(2): 43-50, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27846189
15.
Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(12): 1469-1480, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888833
16.
Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.
Bioorg Med Chem
; 25(20): 5468-5476, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835350
17.
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation.
Drug Metab Rev
; 48(2): 139-58, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27278216
18.
Fully automatic flow-based device for monitoring of drug permeation across a cell monolayer.
Anal Bioanal Chem
; 408(3): 971-81, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26615589
19.
Boldine enhances bile production in rats via osmotic and farnesoid X receptor dependent mechanisms.
Toxicol Appl Pharmacol
; 285(1): 12-22, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25771127
20.
Genetic polymorphisms in metabolic pathways of leflunomide in the treatment of rheumatoid arthritis.
Clin Exp Rheumatol
; 33(3): 426-32, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25664505